Indigo graduated from Johns Hopkins University with a combined Bachelor and Master of Science in Neuroscience (Honors), with an additional major in Cognitive Science. As an undergraduate, he performed neuropathological analysis on postmortem human brain specimens at the Lieber Institute for Brain Development. He received the Emily and Thomas Meren Award for his work as a BS/MS student, researching the biology of extracellular vesicles in neuroimmune homeostasis, with applications to immune dysregulation in neuropsychiatric disorders. He helped investigate cytokine regulation in neuroinflammatory astrocytes by proteins such as glutathione S-transferase mu 1. Additionally, he helped discover the involvement of interleukin-33 in social and anxiety-like behaviors in mice.
In the Liddelow Lab, Indigo is investigating the biology of astrocytes and how they respond to injury and disease.
Dohi E, Choi EY, Rose IVL, Murata AS, Chow S, Niwa M, Kano SI (2017) Behavioral changes in mice lacking interleukin-33. eNeuro 4(6):ENEURO.0147-17.2017. PMID: 29379874.
Kano SI, Dohi E, Rose IVL (2019) Extracellular vesicles for research on psychiatric disorders. Schizophr Bull 45(1):7-16. PMID: 30239909.
Kano SI, Choi EY, Dohi E, Agarwal S, Chang DJ, Wilson AM, Lo BD, Rose IVL, Gonzalez S, Imai T, Sawa A (2019) Glutathione S-transferases promote proinflammatory astrocyte-microglia communication during brain inflammation. Sci Signal 12(569). PMID: 30783009.