ALL PUBLICATIONS

Publications are separated by research theme. The most up-to-date list is at Pubmed or Google Scholar.

Media highlights on recent publications can be found here.

Online searchable databases are available for reactive astrocytes, rodent and human CNS glia and aging astrocytes, and for human iPSC-derived astrocytes on our searchable databases at WWW.GLIASEQ.COM.

 

(* = equal contribution)

2024

  1. [COMMENTARY] Lione F, Liddelow SA (2024) The silence of the reactive astrocytes. Nat Neurosci. PMID: 38424325.

  2. [REVIEW] Liddelow SA, Olsen ML, Sofroniew MV (2024) Reactive astrocytes and emerging roles in Central Nervous System (CNS) disorders. Cold Spring Harb Perspect Biol a041356. PMID: 38316554.

  3. [RESEARCH] Prakash P, Erdjument-Bromage H, O'Dea MR, Munson CN, Labib D, Fossati V, Neubert TA, Liddelow SA (2024) Proteomic profiling of interferon-responsive reactive astrocytes in rodent and human. Glia 72(3):625-642. PMID: 38031883.

  4. [RESEARCH] Prescott K, Munch AE, Brahms E, Weigel MM, Inoue K, Buckwalter MS, Liddelow S, Peterson T (2024) Blocking formation of neurotoxic reactive astrocytes is beneficial following stroke. Front Mol Neurosci 16:1305949. PMID: 38240014.

2023

  1. [PREPRINT] Kim RD, Marchildon AE, Frazel PW, Hasel P, Guo AX, Liddelow SA. Temporal and spatial analysis of astrocytes following stroke identifies novel drivers of reactivity. bioRxiv 2023.11.12.566710.

  2. [RESEARCH] Frazel PW, Labib D, Fisher T, Brosh R, Pirjanian N, Marchildon A, Boeke JD, Fossati V, Liddelow SA (2023) Longitudinal scRNA-seq analysis in mouse and human informs optimization of rapid mouse astrocyte differentiation protocols. Nat Neurosci 26(10):1726-1738. PMID: 37697111. [bioRxiv 471509 [Preprint] July 31, 2023. Available from: https://doi.org/10.1101/2021.12.07.471509].

    >>DATA AVAILABLE here.

  3. [PREPRINT] Lopez-Lee C, Kodama L, Fan F, Wong MY, Foxe NR, Jiaz L, Yu F, Ye P, Zhu J, Norman K, Torres ER, Kim RD, Mousa GA, Dubal D, Liddelow S, Luo W, Gan L. Sex chromosomes and gonads shape the sex-biased transcriptomic landscape in Tlr7-mediated demyelination during aging. bioRxiv 2023.09.19.558439.

  4. [PREPRINT] Frazel P, Fricano-Kugler C, May-Zhang AA, O'Dea MR, Prakash P, Desmet N, Lee H, Meltzer RH, Fontanez K, Hettige P, Lithwick-Yanai G, Lipson D, Luikart BW, Dasen JS, Liddelow SA. Single-cell analysis of the nervous system at small and large scales with instant partitions. bioRxiv 2023.07.14.549051.

  5. [PREPRINT] Hasel P, Cooper ML, Marchildon AE, Rufen-Blanchette UA, Kim RD, Ma TC, Kang UJ, Chao MV, Liddelow SA. Defining the molecular identity and morphology of glia limitans superficialis astrocytes in mouse and human. bioRxiv 2023.04.06.535893.

  6. [REVIEW] Soucy JR, et al. (2023) Retinal ganglion cell repopulation for vision restoration in optic neuropathy: a roadmap from the RReSTORe Consortium. Mol Neurodegener 18(1):64. PMID: 37735444.

  7. [RESEARCH] D'Elia KP, Hameedy H, Goldblatt D, Frazel P, Kriese M, Zhu Y, Hamling KR, Kawakami K, Liddelow SA, Schoppik D, Dasen JS (2023) Determinants of motor neuron functional subtypes important for locomotor speed. Cell Rep 42(9):113049. PMID: 37676768. [bioRxiv 521820 [Preprint] May 16, 2023. Available from: https://doi.org/10.1101/2022.12.23.521820].

  8. [RESEARCH] Castranio EL*, Hasel P*, Haure-Mirande JV, Ramirez Jimenez AV, Hamilton BW, Kim RD, Glabe CG, Wang M, Zhang B, Gandy S, Liddelow SA#, Ehrlich ME# (2023) Microglial INPP5D limits plaque formation and glial reactivity in the PSAPP mouse model of Alzheimer's disease. Alzheimers Dement 19(6):2239-2252. PMID: 36448627.

    >>DATA AVAILABLE here.

  9. [REVIEW] Patani R, Hardingham G, Liddelow SA (2023) The role of reactive astrocytes in inflammation and neurodegeneration. Nat Rev Neurol 19:395-409. PMID: 37308616.

  10. [REVIEW] Kloske CM, Barnum CJ, Batista AF, Bradshaw EM, Brickman AM, Bu G, Dennison J, Gearon MD, Goate AM, Haass C, Heneka MT, Hu WT, Huggins LKL, Jones NS, Koldamova R, Lemere CA, Liddelow SA, Marcora E, Marsh SE, Nielsen HM, Petersen KK, Petersen M, Piña-Escudero SD, Qiu WQ, Quiroz YT, Reiman E, Sexton C, Tansey MG, Tcw J, Teunissen CE, Tijms BM, van der Kant R, Wallings R, Weninger SC, Wharton W, Wilcock DM, Wishard TJ, Worley SL, Zetterberg H, Carrillo MC (2023) APOE and immunity: Research highlights. Alzheimers Dement 19(6):2677-2696. PMID: 36975090.

  11. [REVIEW] Hasel P, Aisenberg WH, Bennett FC, Liddelow SA (2023) Molecular and metabolic heterogeneity of astrocytes and microglia. Cell Metab 35(4):555-570. PMID: 36958329.

  12. [REVIEW] Saunders NR, Dziegielewska KM, Fame RM, Lehtinen MK, Liddelow SA (2023) The choroid plexus: a missing link in our understanding of brain development and function. Physiol Rev 103(1):919-956. PMID: 36173801.

2022

  1. [PREPRINT] Renz P, Surbek D, Haesler V, Huang EJ, Chavali M, Liddelow SA, Rowitch D, Schoeberlein A, Brosius Lutz A. Silencing inflammatory reactive astrocyte activation factors ameliorates disease outcomes in perinatal white matter injury. bioRxiv 2022.12.19.521083.

  2. [RESEARCH] Titus HE, Xu H, Robinson AP, Patel PA, Chen Y, Fantini D, Eaton V, Karl M, Garrison ED, Rose IVL, Chiang MY, Podojil JR, Balabanov R, Liddelow SA, Miller RH, Popko B, Miller SD (2022) Repurposing the cardiac glycoside digoxin to stimulate myelin regeneration in chemically-induced and immune-mediated mouse models of multiple sclerosis. Glia 70(10):1950-1970. PMID: 35809238.

  3. [RESEARCH] Fernández-Castañeda A, Lu P, Geraghty AC, Song E, Lee MH, Wood J, O'Dea MR, Dutton S, Shamardani K, Nwangwu K, Mancusi R, Yalçın B, Taylor KR, Acosta-Alvarez L, Malacon K, Keough MB, Ni L, Woo PJ, Contreras-Esquivel D, Toland AMS, Gehlhausen JR, Klein J, Takahashi T, Silva J, Israelow B, Lucas C, Mao T, Peña-Hernández MA, Tabachnikova A, Homer RJ, Tabacof L, Tosto-Mancuso J, Breyman E, Kontorovich A, McCarthy D, Quezado M, Vogel H, Hefti MM, Perl DP, Liddelow S, Folkerth R, Putrino D, Nath A, Iwasaki A, Monje M (2022) Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation. Cell 185(14):2452-2468. PMID: 35768006.

  4. [RESEARCH] Sadick JS*, O'Dea MR*, Hasel P, Dykstra T, Faustin A, Liddelow SA (2022) Astrocytes and oligodendrocytes undergo subtype-specific transcriptional changes in Alzheimer's disease. Neuron 110(11):1788-1805. PMID: 35381189.

  5. [RESEARCH] Labib D, Wang Z, Prakash P, Zimmer M, Smith MD, Frazel PW, Barbar L, Sapar ML, Calabresi PA, Peng J, Liddelow SA, Fossati V (2022) Proteomic alterations and novel markers of neurotoxic reactive astrocytes in human induced pluripotent stem cell models. Front Mol Neurosci 15:870085. PMID: 35592112.

  6. [RESEARCH] Kleffman K, Levinson G, Rose IVL, Blumenberg LM, Shadaloey SAA, Dhabaria A, Wong E, Galan-Echevarria F, Karz A, Argibay D, Von Itter R, Floristan A, Baptiste G, Eskow NM, Tranos JA, Chen J, Vega Y Saenz de Miera EC, Call M, Rogers R, Jour G, Wadghiri YZ, Osman I, Li YM, Mathews P, DeMattos R, Ueberheide B, Ruggles KV, Liddelow SA, Schneider RJ, Hernando E (2022) Melanoma-secreted amyloid beta suppresses neuroinflammation and promotes brain metastasis. Cancer Discov 12(5):1314-1335. PMID: 35262173. [bioRxiv 854885 [Preprint] November 26, 2019. Available from: https://doi.org/10.1101/854885].

  7. [RESEARCH] Bandler RC, Vitali I, Delgado RN, Ho MC, Dvoretskova E, Ibarra Molinas JS, Frazel PW, Mohammadkhani M, Machold R, Maedler S, Liddelow SA, Nowakowski TJ, Fishell G, Mayer C (2022) Single-cell delineation of lineage and genetic identity in the mouse brain. Nature 601(7893):404-409. PMID: 34912118.

  8. [REVIEW] Wareham L, Liddelow SA, Temple S, Benowitz LI, Di Polo A, Wellington C, Goldberg J, He Z, Duan X, Bu G, Davis AA, Shekhar K, La Torre A, Chang DC, Canto-Soler MV, Flanagan JG, Subramanian P, Rossi S, Brunner T, Bovenkamp DE, Calkins DJ. (2022) Solving neurodegeneration: common mechanisms and strategies for new treatments. Mol Neurodegen 17(1):23. PMID: 35313950.

  9. [REVIEW] Saunders NR, Dziegielewska KM, Fame RM, Lehtinen MK, Liddelow SA (2022) The choroid plexus: a missing link in our understanding of brain development and function. Physiol Rev 103(1):919-956. PMID: 36173801.

2021

  1. [RESEARCH] Guttenplan KA, Weigel MK*, Prakash P*, Wijewardhane PR, Hasel P, Rufen-Blanchette U, Münch AE, Blum JA, Fine J, Neal MC, Bruce KD, Gitler AD, Chopra G, Liddelow SA, Barres BA (2021) Neurotoxic reactive astrocytes induce cell death via saturated lipids. Nature 599(7883):102–107. PMID: 34616039.

  2. [RESEARCH] Hasel P, Rose IVL, Sadick JS, Kim RD, Liddelow SA (2021) Neuroinflammatory astrocyte subtypes in the mouse brain. Nat Neurosci 24(10):1475-1487. PMID: 34413515.

    >>DATA AVAILABLE here.

  3. [RESEARCH] Prakash P*, Jethava KP*, Korte N*, Izquierdo P*, Favuzzi E, Rose IVL, Guttenplan KA, Manchanda P, Dutta S, Rochet JC, Fishell G, Liddelow SA, Attwell D, Chopra G (2021) Monitoring phagocytic uptake of amyloid β into glial cell lysosomes in real time. Chem Sci 12(32):10901-10918. PMID: 34476070. [bioRxiv 002857 [Preprint] March 29, 2020. Available from: https://doi.org/10.1101/2020.03.29.002857].

  4. [RESEARCH] Marzan DE, Brügger-Verdon V, West BL, Liddelow S, Samanta J, Salzer JL (2021) Activated microglia drive demyelination via CSF1R signaling. Glia 69(6):1583-1604. PMID: 33620118.

  5. [COMMENTARY] Kwon AHK, Liddelow SA (2021) Astrocytes have a license to kill inflammatory T cells. Immunity 54(4):614-616. PMID: 33852828.

  6. [REVIEW] Hasel P, Liddelow SA (2021) Astrocytes. Curr Biol 31(7):R326-R327. PMID: 33848482.

  7. [COMMENTARY] Hasel P, Liddelow SA (2021) Isoform-dependent APOE secretion modulates neuroinflammation. Nat Rev Neurol 17(5):265-266. PMID: 33727705.

  8. [REVIEW] Han RT*, Kim RD*, Molofsky AV, Liddelow SA (2021) Astrocyte-immune cell interactions in physiology and pathology. Immunity 54(2):211-224. PMID: 33567261.

2020

  1. [RESEARCH] Zhang J, Velmeshev D, Hashimoto K, Huang YH, Hofmann JW, Shi X, Chen J, Leidal AM, Dishart JG, Cahill MK, Kelley KW, Liddelow SA, Seeley WW, Miller BL, Walther TC, Farese RV Jr, Taylor JP, Ullian EM, Huang B, Debnath J, Wittmann T, Kriegstein AR, Huang EJ (2020) Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency. Nature 588(7838):459-465. PMID: 32866962.

  2. [RESEARCH] Guttenplan KA, Weigel MK, Adler DI, Couthouis J, Liddelow SA*, Gitler AD*, Barres BA* (2020) Knockout of reactive astrocyte activating factors slows disease progression in an ALS mouse model. Nat Commun 11(1):3753. PMID: 32719333.

    >>DATA AVAILABLE here.

  3. [RESEARCH] Guttenplan KA, Stafford BK, El-Danaf RN, Adler DI, Münch AE, Weigel MK, Huberman AD, Liddelow SA (2020) Neurotoxic reactive astrocytes drive neuron death after retinal injury. Cell Rep 31(12):107776. PMID: 32579912.

  4. [RESEARCH] Barbar L, Jain T, Zimmer M, Kruglikov I, Sadick JS, Wang M, Kalpana K, Rose IVL, Burstein SR, Rusielewicz T, Nijsure M, Guttenplan KA, di Domenico A, Croft G, Zhang B, Nobuta H, Hébert JM, Liddelow SA, Fossati V (2020) CD49f Is a novel marker of functional and reactive human iPSC-derived astrocytes. Neuron 107(3):436-453. PMID: 32485136. [bioRxiv 678359 [Preprint] June 21, 2019. Available from: https://doi.org/10.1101/678359].

    >>DATA AVAILABLE here.

  5. [RESEARCH] Sadick JS, Crawford LA, Cramer HC 3rd, Franck C, Liddelow SA, Darling EM (2020) Generating cell type-specific protein signatures from non-symptomatic and diseased tissues. Ann Biomed Eng 48(8):2218-2232. PMID: 32303872.

    >>DATA AVAILABLE here.

  6. [RESEARCH] Ineichen BV, Di Palma S, Laczko E, Liddelow SA, Neumann S, Schwab ME, Mosberger AC (2020) Regional differences in penetration of the protein stabilizer Trimethoprim (TMP) in the rat central nervous system. Front Mol Neurosci 13:167. PMID: 33013318.

  7. [REVIEW] Spanos F, Liddelow SA (2020) An overview of astrocyte responses in genetically induced Alzheimer's disease mouse models. Cells 9(11):2415. PMID: 33158189.

  8. [REVIEW] Liddelow SA*, Marsh SE*, Stevens B* (2020) Microglia and astrocytes in disease: dynamic duo or partners in crime? Trends Immunol 41(9):820-835. PMID: 32819809.

  9. [COMMENTARY] Liddelow SA (2020) Don’t you know that you’re ToxSeq? Nat Immunol 21(5):495–497. PMID: 32284595.

2019

  1. [RESEARCH] Joshi AU, Minhas PS, Liddelow SA, Haileselassie B, Andreasson KI, Dorn GW 2nd, Mochly-Rosen D (2019) Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration. Nat Neurosci 22(10):1635-1648. PMID: 31551592.

  2. [RESEARCH] Hartmann K, Sepulveda-Falla D, Rose IVL, Madore C, Muth C, Matschke J, Butovsky O, Liddelow S, Glatzel M, Krasemann S (2019) Complement 3+-astrocytes are highly abundant in prion diseases, but their abolishment led to an accelerated disease course and early dysregulation of microglia. Acta Neuropathol Commun 7(1):83. PMID: 31118110.

  3. [RESEARCH] Gibson EM, Nagaraja S, Ocampo A, Tam LT, Wood LS, Pallegar PN, Greene JJ, Geraghty AC, Goldstein AK, Ni L, Woo PJ, Barres BA, Liddelow S, Vogel H, Monje M (2019) Methotrexate chemotherapy induces persistent tri-glial dysregulation that underlies chemotherapy-related cognitive impairment. Cell 176(1-2):43-55. PMID: 30528430.

  4. [COMMENTARY] Bennett FC, Liddelow SA (2019) Microglia metabolic breakdown drives Alzheimer's pathology. Cell Metab 30(3):405-406. PMID: 31484050.

  5. [COMMENTARY] Liddelow SA, Sofroniew MV (2019) Astrocytes usurp neurons as a disease focus. Nat Neurosci 22(4):512-513. PMID: 30858602.

  6. [REVIEW] Sadick JS, Liddelow SA (2019) Don't forget astrocytes when targeting Alzheimer's disease. Br J Pharmacol 176(18):3585-3598. PMID: 30636042.

  7. [REVIEW] Liddelow SA (2019) Modern approaches to investigating non-neuronal aspects of Alzheimer’s disease. FASEB J 33(2):1528-1535. PMID: 30703873.

  8. [REVIEW] Guttenplan KA, Liddelow SA (2018) Astrocytes and microglia: Models and tools. J Exp Med 216(1):71-83. PMID: 30541903.

2018

  1. [RESEARCH] Lananna BV, Nadarajah CJ, Izumo M, Cedeño MR, Xiong DD, Dimitry J, Tso CF, McKee CA, Griffin P, Sheehan PW, Haspel JA, Barres BA, Liddelow SA, Takahashi JS, Karatsoreos IN, Musiek ES (2018) Cell-autonomous regulation of astrocyte activation by the circadian clock protein BMAL1. Cell Rep 25(1):1-9. PMID: 30282019. [bioRxiv 362814 [Preprint] July 5, 2018. Available from: https://doi.org/10.1101/362814].

  2. [RESEARCH] Yun SP, Kam TI, Panicker N, Kim S, Oh Y, Park JS, Kwon SH, Park YJ, Karuppagounder SS, Park H, Kim S, Oh N, Kim NA, Lee S, Brahmachari S, Mao X, Lee JH, Kumar M, An D, Kang SU, Lee Y, Lee KC, Na DH, Kim D, Lee SH, Roschke VV, Liddelow SA, Mari Z, Barres BA, Dawson VL, Lee S, Dawson TM, Ko HS (2018) Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease. Nature Med 24(7):931–938. PMID: 29892066.

  3. [RESEARCH] Clarke LE, Liddelow SA, Chakraborty C, Münch AE, Heiman M, Barres BA (2018) Normal aging induces A1-like astrocyte reactivityProc Natl Acad Sci USA 115(8):E1896-E1905. PMID: 29437957.

    >>DATA AVAILABLE here.

  4. [RESEARCH] Vainchtein ID, Chin G, Cho FS, Kelley KW, Miller JG, Chien EC, Liddelow SA, Nguyen PT, Nakao-Inoue H, Dorman LC, Akil O, Joshita S, Barres BA, Paz JT, Molofsky AB, Molofsky AV (2018) Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit developmentScience 359(6381):1269-1273. PMID: 29420261.

  5. [COMMENTARY] Guttenplan KA, Liddelow SA (2017) Play It Again, SAM: Macrophages control peripheral fat metabolismTrends Immunol 39(2):81-82. PMID: 29290566.

  6. [COMMENTARY] Liddelow SA (2017) Perspective: Bypassing the barrier: new routes for delivery of macromolecules to the central nervous systemJ Physiol 596(3):361-362. PMID: 29171665.

2017 AND EARLIER

  1. [RESEARCH] Liddelow SA, Guttenplan KA, Clarke LE, Bennett FC, Bohlen CJ, Schirmer L, Bennett ML, Münch AE, Chung W-S, Peterson TC, Wilton DK, Frouin A, Napier BA, Panicker N, Kumar M, Dawson VL, Dawson TM, Buckwalter MS, Rowitch DH, Stevens B, Barres BA (2017) Neurotoxic reactive astrocytes are induced by activated microglia. Nature 541(7638):481-487. PMID: 28099414.

  2. [RESEARCH] Shi Y, Yamada K, Liddelow SA, Smith ST, Zhao L, Luo W, Tsai R, Spina S, Grinberg L, Rojas J, Gallardo G, Wang K, Roh J, Robinson G, Finn MB, Jiang H, Sullivan P, Wood M, Baufeld C, Wood M, Sutphen C, McCue L, Xiong C, Del-Aguila J, Morris J, Cruchaga C, Fagan A, Miller B, Boxer B, Seeley W, Butovsky O, Barres B, Paul S, Holtzman D (2017) ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy. Nature 549(7673):523-527. PMID: 28959956.

  3. [COMMENTARY] Clarke LE, Liddelow SA (2017) Neurobiology: Diversity reaches the starsNature 548(7668):396–397. PMID: 28836597.

  4. [REVIEW] Liddelow SA, Barres BA (2017) Reactive astrocytes: production, function, and therapeutic potentialImmunity 46(6):957-967. PMID: 28636962.

  5. [RESEARCH] Bennett ML, Bennett FC, Liddelow SA, Ajami B, Zamanian JL, Fernhoff NB, Mulinyawe SB, Bohlen CJ, Adil A, Tucker A, Weissman IL, Chang EF, Li G, Grant GA, Hayden-Gephart M, Barres BA (2016) New tools for studying microglia in the mouse and human CNSProc Natl Acad Sci USA 113(12):E1738-1746. PMID: 26884166.

    >>DATA AVAILABLE here.

  6. [COMMENTARY] Liddelow SA, Barres BA (2016) Not everything is scary about a glial scar. Nature 32(7598):182-183. PMID: 27027287.

  7. [REVIEW] Liddelow SA, Hoyer D (2016) Astrocytes: adhesion molecules and immunomodulation. Curr Drug Targets 17(16):1871-1881. PMID: 26721411.

  8. [REVIEW] Stolp HB, Liddelow SA, Saunders NR (2016) Editorial: Ontogeny and Phylogeny of Brain Barrier Mechanisms. Front Neurosci 10:41. PMID: 26909020.

  9. [REVIEW] Liddelow SA, Barres BA (2015) SnapShot: Astrocytes in health and disease. Cell 162(5):1170-1170.e1. PMID: 26317476.

  10. [REVIEW] Liddelow SA (2015) Development of the choroid plexus and blood-CSF barrier. Front Neurosci 9:32. PMID: 25784848.

  11. [RESEARCH] Saunders NR, Dziegielewska KM, Møllgård K, Habgood MD, Wakefield MJ, Lindsay H, Stratzielle N, Ghersi-Egea JF, Liddelow SA (2015) Influx mechanisms in the embryonic and adult rat choroid plexus: a transcriptome study. Front Neurosci 9:123. PMID: 25972776.

  12. [RESEARCH] Whish S, Dziegielewska KM, Møllgård K, Noor NM, Liddelow SA, Habgood MD, Richardson SJ, Saunders NR (2015) The inner CSF-brain barrier: developmentally controlled access to the brain via intercellular junctions. Front Neurosci 9:16. PMID: 25729345.

  13. [RESEARCH] Zhang Y, Chen K, Sloan SA, Bennett ML, Scholze AR, O'Keeffe S, Phatnani HP, Guarnieri P, Caneda C, Ruderisch N, Deng S, Liddelow SA, Zhang C, Daneman R, Maniatis T, Barres BA, Wu JQ (2014) An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortexJ Neurosci 34(36):11929-11947. PMID: 25186741.

    >>DATA AVAILABLE here.

  14. [RESEARCH] Saunders NR, Noor NM, Dziegielewska KM, Wheaton BJ, Liddelow SA, Steer DL, Ek CJ, Habgood MD, Wakefield MJ, Lindsay H, Truettner J, Miller RD, Smith AI, Dietrich WD (2014) Age-dependent transcriptome and proteome following transection of neonatal spinal cord of Monodelphis domestica (South American Grey Short-Tailed Opossum). PLoS ONE 9(6):e99080. PMID: 24914927.

  15. [RESEARCH] Liddelow SA, Dzięgielewska KM, Møllgård K, Whish SC, Noor NM, Wheaton BJ, Gehwolf R, Wagner A, Traweger A, Bauer H, Bauer HC, Saunders NR (2014) Cellular specificity of the blood-CSF barrier for albumin transfer across the choroid plexus epithelium. PLoS ONE 9(9):e106592. PMID: 25211495.

  16. [RESEARCH] Kratzer I, Liddelow SA, Saunders NR, Dziegielewska KM, Strazielle N, Ghersi-Egea J-F (2013) Developmental changes in the transcriptome of the rat choroid plexus in relation to neuroprotection. Fluids Barriers CNS 10(1):25. PMID: 23915922.

  17. [RESEARCH] Liddelow SA, Dziegielewska KM, Ek CJ, Habgood MD, Bauer H, Bauer H-C, Lindsay H, Wakefield MJ, Ghersi-Egea J-F, Strazielle N, Kratzer I, Møllgård K, Saunders NR (2013) Mechanisms that determine the internal environment of the developing brain: a transcriptomic, functional and ultrastructural approach. PLoS ONE 8(7):e65629. PMID: 23843944.

  18. [REVIEW] Stolp HB, Liddelow SA, Sá-Pereira I, Dziegielewska KM, Saunders NR (2013) Immune responses at brain barriers and implications for brain development and neurological function in later life. Front Integr Neurosci 7:61. PMID: 23986663.

  19. [REVIEW] Saunders NR, Daneman R, Dziegielewska KM, Liddelow SA (2013) Transporters of the blood-brain and blood-CSF interfaces in development and in the adult. Mol Aspects Med 34(2-3):742–752. PMID: 23506907.

  20. [RESEARCH] Liddelow SA, Temple S, Møllgård K, Gehwolf R, Wagner A, Bauer J, Bauer H-C, Phoenix TN, Dziegielewska KM, Saunders NR (2012) Molecular characterisation of transport mechanisms at the developing mouse blood-CSF interface: a transcriptome approach. PLoS ONE 7(3): e33554. PMID: 22457777.

  21. [REVIEW] Saunders NR, Liddelow SA, Dziegielewska KM (2012) Barrier mechanisms in the developing brain. Front Pharmacol 3:46. PMID: 22479246.

  22. [RESEARCH] Liddelow SA, Dziegielewska KM, Møllgård K, Phoenix TN, Temple S, VandeBerg JL, Saunders NR (2011) Sparc/osteonectin, and endogenous mechanism for targeting albumin to the blood-CSF interface during brain development. Eur J Neurosci 34(7):1062-1073. PMID: 21899600.

  23. [RESEARCH] Liddelow SA, Dziegielewska KM, VandeBerg JL, Noor NM, Potter AM, Saunders NR (2011) Modification of protein transfer across blood/cerebrospinal fluid barrier in response to altered plasma protein composition during development. Eur J Neurosci 13(3):391-400. PMID: 21138490.

  24. [REVIEW] Liddelow SA (2011) Fluids and Barriers of the CNS: a historical viewpoint. Cerebrospinal Fluid Res 8(1):2. PMID: 21349150.

  25. [REVIEW] Saunders NR, Ek CJ, Habgood MD, Johansson PA, Liddelow SA, Dziegielewska KM (2011) Assessing blood-CSF barrier function in the rat embryo. In: The blood-CSF barrier, biology and research protocols. Ed. Nag S. Humana Press, New Jersey.

  26. [RESEARCH] Liddelow SA, Dziegielewska KM, VandeBerg JL, Saunders NR (2010) Development of the lateral ventricular choroid plexus in a marsupial, Monodelphis domestica. Cerebrospinal Fluid Res 7:16. PMID: 20920364.

  27. [RESEARCH] Ek CJ, Wong A, Liddelow SA, Johansson PA, Dziegielewska KM, Saunders NR (2010) Efflux mechanisms at the developing brain barriers: ABC-transporters in the fetal and postnatal rat. Toxicol Lett 197(1):51-59. PMID: 20466047.

  28. [COMMENTARY] Bueter W, Saunders NR, Mallard C, Bauer HC, Stolp HB, Kavelaars A, Dammann O, NEUROBID consortium (Dammann O, Stangel M, Bueter W, Brinkhaus MJ, McGuinness N, Gressens P, Ghersi-Egea JF, Heijen C, Kavelaars A, Molnár Z, Stolp H, Anthony D, Johnson T, Neuhoff S, Saunders N, Dziegielewska K, Ek J, Liddelow S, Mallard C, Säcman K, Förster C, Speer C, Kleinschnitz C, Neuhaus W, Burek M, Strazielle N, Bauer HC, Bauer H) (2010) NEUROBID – an EU-funded project to study the developing brain barriers. Int J Dev Neurosci 28(5):411-412. PMID: 20412847.

  29. [RESEARCH] Liddelow SA, Dziegielewska KM, Ek CJ, Johansson PA, Potter AM, Saunders NR (2009) Cellular transport of macromolecules across the developing choroid plexus of Monodelphis domestica. Eur J Neurosci 29(2):253-266. PMID: 19200232.

  30. [REVIEW] Johansson PA, Dziegielewska KM, Liddelow SA, Saunders NR (2008) The blood-CSF barrier explained: when development is not immaturity. BioEssays 30(3):237-248. PMID: 18293362.

  31. [RESEARCH] Johansson PA, Dziegielewska KM, Ek CJ, Habgood MD, Liddelow SA, Potter AM, Stolp HB, Saunders NR (2006) Blood-CSF barrier function in the rat embryo. Eur J Neurosci 24(1):65-76. PMID: 16800861.