XINRUO (AMY) GUO

MD/PhD STUDENT

xinruo.guo@nyulangone.org | @AmyXGuo1

Amy was born and raised in Beijing, China, and at age 17, she moved to Boston, Massachusetts, with her family. Amy studied Biochemistry at Tufts University as an undergraduate and graduated with Summa Cum Laude and several departmental awards. She was working at Dr. Krishna Kumar’s lab designing novel diabetes therapeutics with increased bioavailability. After graduating from college, she worked as a research associate at Dr. Feng Zhang’s lab, where she explored the molecular basis for autism spectrum disorder in neuronal and glial cells using novel in vivo perturbation models.

As an MD/PhD student at NYU School of Medicine, Amy is planning to investigate the homeostasis of astrocytes in injury and disease models and reversibility of reactive astrocytes and their effects on surrounding cell types.

Outside of the lab and clinics, she is a food connoisseur, an outdoor climber, and a world traveler. In her free time, she enjoys exploring new restaurants and hanging out with family and friends.

Amy is a recipient of Medical Scientist Training Program (T32) from NIH.   

Amy is a recipient of Alzheimer's disease research center (ADRC) REC junior scholar for 2024-2025.

KEY PUBLICATIONS

  1. Jin X, Simmons SK, Guo A, Shetty AS, Ko M, Nguyen L, Jokhi V, Robinson E, Oyler P, Curry N, Deangeli G, Lodato S, Levin JZ, Regev A, Zhang F, Arlotta P (2020) In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes. Science 370(6520): eaaz6063. PMID: 33243861.

  2. Guo AX, Job A, Pacione D, Agrawal N. (2024) Risk of intracranial meningioma in patients with acromegaly: a systematic review. Front Endocrinol.;15. PMID: 38919490.

  3. Kim RD, Marchildon AE, Frazel PW, Hasel P, Guo AX, Liddelow SA (2023) Temporal and spatial analysis of astrocytes following stroke identifies novel drivers of reactivity. BioRxiv. PMID: 38014211